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Showing posts with label immunity. Show all posts
Showing posts with label immunity. Show all posts

Monday, December 18, 2023

Protect yourself and your community from disease; Remember to wash your hands

Getting vaccinated is not just about ensuring you don’t fall ill, but also about saving those around you from getting sick.


— Graphics: Positive Parenting This is how an infectious disease with an r-naught of four spreads from one patient.

herd immunity




VACCINATION directly protects individuals who are vaccinated against certain infections, but it can also provide indirect protection to the unvaccinated in a population.

This is what we call herd immunity or community immunity. It is a key aspect of epidemic control.

To understand herd immunity, we need to be familiar with certain terms.

Firstly, we have to know the infectiousness of a disease, indicated by its basic reproduction number (R-naught or R0).

This can be defined as the expected number of new infections generated by one infectious individual in a fully vulnerable population without any control measures.

For example, an infectious disease with an R-naught of four means that one case is expected to generate four other cases.

The higher the R-naught, the more infectious the disease is.

Each infectious disease has its own R-naught and it may vary across populations and over time, depending on various factors.

The R-naught in turn determines the herd immunity threshold (HIT), which is the minimum level of vaccination coverage or minimum number of immune individuals in a population that must be achieved to produce herd immunity against a certain infection.

An easy way to calculate HIT is by using this equation: HIT = 1 – 1/R-naught.

Hence, to achieve herd immunity against a disease with R-naught of four, at least 3/4 or 75% of the population have to be immunised.

This calculation assumes that susceptible and infectious individuals in a population are equally in contact with one another and spread the infection in the same way.

From this, we can deduce that the more infectious the disease, the higher the R-naught, and thus, the higher the HIT, and the more the people that need to be vaccinated to achieve herd immunity in a population.

When enough people are vaccinated against a particular disease, they will be able to ‘protect’ those who are unable to be vaccinated from those who are infected.

For optimal benefit


Various other factors play crucial roles to ensure that optimal herd immunity can be achieved via vaccination.

They include:

> High vaccine effectiveness


This is key to attaining optimal herd immunity.

Vaccine effectiveness varies between different populations and regions.

However, not all vaccines stimulate lifelong immunity and this may decrease herd immunity over time.

The effect of waning immunity can be mitigated by increasing vaccination coverage or taking booster shots. >

Reduced transmission potential (or force of infection)

Vaccination efforts need to target the main reservoir of infection, i.e. groups who are most likely to get and spread the infection.

Low vaccine coverage among these groups may compromise herd immunity, even though overall coverage is high.

This also depends on the route of transmission of the pathogen.

> Appropriate vaccine uptake

Optimal herd immunity is more likely to be achieved when vaccine coverage is at the higher end of the HIT.

Another important factor is appropriate distribution patterns.

This can be achieved by targeting those who are highly exposed to the infection (e.g. healthcare workers) and vulnerable populations (e.g. infants and the elderly).

The timeliness in receiving the vaccine also impacts the effectiveness of the vaccination programme, and thus, herd immunity.

For example, in the United Kingdom, the occurrence of invasive pneumococcal disease in unvaccinated adults aged over 65 years has been reduced by 81% after the pneumococcal conjugate vaccine (PCV) was included as part of routine immunisation for infants under two years old.

Protecting the vulnerable

The best-case scenario is to have 100% vaccine effectiveness and coverage, but the reality is far from perfect.

No vaccine is 100% effective, and there are people who cannot get vaccinated or do not elicit strong immune responses from vaccines.

These include newborns, people allergic to certain vaccines, people with weakened or failing immune systems, or elderly with chronic diseases.

This is where herd immunity comes into play, providing indirect protection to these groups.

Optimal herd immunity via vaccination also counteracts waning immunity.

Protection with certain vaccines can diminish with time, e.g. pertussis vaccination starts to weaken after two years.

Thus, people with waning immunity are exposed to infection unless herd immunity is strong and vaccine uptake is sustained.

Apart from the vulnerable population, the following groups of people should also get vaccinated:

> Families and close contacts of those considered as vulnerable

> Caregivers of children, elderly

and sick patients > Healthcare or hospital workers.

When you get yourself vaccinated, you’re not only protecting yourself, but also your loved ones and other vulnerable individuals in the population.

As you can see now, vaccination is crucial and the safest way to achieve optimal herd immunity!


 Datuk Dr Musa Mohd  a paediatrician and Universiti Putra Malaysia lecturer. Datuk Dr Musa Mohd Nordin is a consultant paediatrician and neonatologist. This article is courtesy of the Malaysian Paediatric Association’s Positive Parenting programme in collaboration with expert partners. For further information, please email starhealth@thestar.com.my. The information provided is for educational and communication purposes only, and it should not be construed as personal medical advice. Information published in this article is not intended to replace, supplant or augment a consultation with a health professional regarding the reader’s own medical care. The Star does not give any warranty on accuracy, completeness, functionality, usefulness or other assurances as to the content appearing in this column. The Star disclaims all responsibility for any losses, damage to property or personal injury suffered directly or indirectly from reliance on such information.

The Star Malaysia17 Dec 2023By Dr HUSNA MUSA and Datuk Dr MUSA MOHD NORDIN
By Dr HUSNA MUSA and Datuk Dr MUSA MOHD NORDIN

https://www.thestar.com.my/news/nation/2023/12/17/remember-to-wash-your-hands

Tuesday, November 7, 2023

Digestive Health & Immunity

 





What is the immune system?

Our immune system is made up of many different organs which contribute to our immunity:

Normal Skin vs Damage Skin
Our skin prevents pathogens from entering our body

 

Various internal organs (e.g. bone marrow, spleen, lymph nodes) produce cells/antibodies that specifically target pathogens.

Good Bacteria and Bad Bacteria

The digestive system helps defend against pathogens entering via the gastrointestinal tract. The digestive & immune systems work together to signal immune cells. The gut is also the largest immune organ in human body. The gut microbiota, which are the microbes living in the gut, enhances immunity by forming a protective barrier and signalling (communicating) with immune cells. Good bacteria (gut microbiota) also helps your body digest food and supports your child’s immune system. Keys to good digestive health:

Consume balanced, nutrient-dense diet rich in fruits, vegetables and whole grains

Eat a variety of food as they provide important vitamins, minerals, and dietary fibre. Some vegetables also contain prebiotics (i.e. indigestible fibres that good bacteria feed on). This will contribute to optimal digestive health, which in turn helps improve the digestive process.

Exercise & hydrate

Helps improve diversity of gut microbiota. Try simple exercises, e.g. brisk walking around the house compound or indoor exercises such as stationary bike workouts, yoga, tai chi, and light stretching exercises.

Drink plenty of water to stay well-hydrated. Exercise and staying hydrated help ensure proper food digestion, bowel movement and also helps maintain a healthy balance of good vs bad bacteria.

Manage stress & get enough sleep

Stress and lack of sleep can negatively affect both digestive health and mental wellbeing. To prevent this, manage stress effectively and get sufficient sleep daily.

Include probiotic-rich foods in our diet

This includes food such as cultured milk drinks, yoghurt that contains probiotic live cultures, and fermented food (e.g. kimchi, sauerkraut, tempeh). Studies have found that probiotics promote good digestive health and can both directly and indirectly enhance our immune system.

Take oral nutritional supplements with live probiotic cultures

Supplementing your probiotic intake is usually not a worry. It is good to consult your doctor first to learn if supplementation is necessary and to see the most suitable probiotic supplement for you or your family.

How probiotics help:

  • Inhibits pathogenic (bad) bacteria by competing for nutrients.
  • Forms a protective barrier preventing harmful pathogens from entering our body.
  • Modulates our body’s immune responses (e.g. stimulates production of antibodies, signals immune cells) in response to infection.

Tips for consuming probiotics:

  • The probiotic strain in a product or supplement must be clinically proven and supported by studies and data that show the safety and efficacy of the product. E.g. Bifidobacterium lactis BB-12 and Lactobacillus paracasei L.CASEI 431.
  • Choose products with minimal or no added sugar.
  • Store probiotic products properly to optimise their effectiveness. This helps to maximise the viability of live strains before consumption. Some products require no refrigeration while others need to be refrigerated.
  • Consult your doctor for further information.

Related post:


Sunday, June 21, 2020

When A Stroke Strikes

Physiotherapy for stroke patients is not just about exercises and movement, but also incorporates technology such as functional electrical stimulation and virtual reality. — Photos: SUNWAY MEDICAL CENTRE VELOCITY

There you are, walking around the house, maybe on your way to get something to eat or to the living room to watch some TV.

All of a sudden, one side of your body goes numb and weak, and you lose your balance, causing you to collapse on the floor.

When you try to call for help, you find that you can’t speak properly with your speech sounding slurred.

You realise that you can’t see properly either, as your vision has become blurry.

And when you look at your face in the mirror, you realise that one side is drooping down, but not the other.

You are most likely experiencing a stroke, the third most common cause of death in Malaysia.

This emergency condition occurs when the brain is deprived of vital oxygen supply, either when a blood clot blocks off a blood vessel supplying the brain (ischaemic stroke) or when one of these blood vessels ruptures and starts bleeding (haemorrhagic stroke).

According to consultant neurologist Dr Kok Chin Yong. your brain cells will start to die within minutes after the stroke hits you – about 2,000,000 cells every minute.

Therefore, you need to get help and go to the nearest hospital’s emergency department as soon as possible.

The good news is that there are immediate treatments that can not only save your life, but also minimise any disability you might have from the stroke.

Ischaemic strokes are the most common type of stroke, comprising three-quarters of all cases.

For this type of stroke, the first and most immediate treatment is the administration of tissue plasminogen activators (tPAs), which help break down blood clots.

Says Dr Kok: “For an ischaemic stroke, the target is to unblock the blood clot as soon as possible.

“We can do this with an intravenous (IV) clot-busting agent called alteplase.

“The current guidelines state a cut-off point of 4.5 hours from the onset of symptoms in order to derive benefit from this treatment.

“Hence, time is brain.”

He notes that alteplase is the only US Food and Drug Administration-approved tPA for acute ischaemic stroke at the moment.

Another treatment available in certain hospitals, he adds, is a clot-removal procedure called mechanical thrombectomy, which is done by an interventional radiologist.

Meanwhile, haemorrhagic strokes are usually treated by the neurosurgeon or interventional radiologist.

Explains consultant neurosurgeon Dr Gerard Arvind Martin: “Choosing whether to take the patient to the operating room or not can depend on various factors, such as age and condition of the patient, the level of consciousness and extent of bleeding, all of which the surgeon takes into consideration before performing surgery.

“In those cases where a subarachnoid haemorrhage has occurred due to a suspected aneurysmal rupture, a further scan called an angiogram will be required to determine precisely the site of bleeding.

“Angiograms can be either via computed tomography (CT) scan or a catheter, which is typically carried out by a radiologist in an angiogram suite.

“Depending on the findings, the surgeon can then elect to operate and clip the ruptured aneurysm, or consider endovascular techniques, which are performed by an interventional radiologist.”

If you are lucky, you would have survived your stroke with no or minor complications and have a quick recovery.

However, many stroke survivors will face long-term disability, which can be physical or cognitive.

For example, patients may experience paralysis of the side affected by the stroke; weak coordination; difficulty in speaking, understanding, reading and writing; and difficulty concentrating.

This is where rehabilitation comes in.

A stroke patient exercises his muscles with the help of a machine, supervised by a physiotherapist.
A stroke patient exercises his muscles with the help of a machine, supervised by a physiotherapist.
Physiotherapy Treatment in Malaysia

https://youtu.be/PYQO3SDe8_w


Dr Wong Yee Choon - Mix FM Doctor On Call

How much you know about Stroke? Stroke is an emergency, every minute counts – Act F.A.S.T.
Listen to Dr Wong Yee Choon, consultant Neurologist being interviewed by Mix FM - Doctor On Call.
Topic: Stroke - Act F.A.S.T

https://www.facebook.com/PantaiHospitalPenang/videos/1806467726066530/


Says Dr Kok: “This is an area that is often given less attention, when in fact, to me, it is equally important as the acute treatment for stroke.

 “A good rehabilitation programme improves disability and prevents complications.”

According to Sunway Medical Centre Velocity Rehabilitation Centre head Maxim Chea, stroke rehabilitation has to be individualised to the patient as it depends on the part of the body or type of ability affected by the stroke.

He explains that there are three main types of rehabilitation therapy: physical therapy, technology-assisted physical therapy (e.g. functional electrical stimulation and virtual reality), and cognitive and emotional therapy.

Visual rehabilitation is also available for those whose vision is affected by stroke.

For example, consultant neuro-ophthalmologist Dr Lakana Kumar shares that “Double vision and peripheral loss of vision can be treated with prisms incorporated into glasses for patients to wear.”

Rehabilitation is usually carried out by a team consisting of physiotherapists, occupational therapists, speech therapists, and dieticians/nutritionists, among others.

In addition to physical and cognitive problems, patients might easily become depressed, overly anxious and panic easily.

Says consultant psychiatrist Dr Lim Wai Jenn: “Stroke survivors are at significantly higher risk for neuropsychiatric conditions such as post-stroke depression (one in three patients), anxiety (one in four patients), and other changes in personality and behaviour.

“These conditions impede the rehabilitation process and degree of recovery in post-stroke patients.

“They also significantly impact the patients’ long-term functioning and quality of life, and can even lead to higher mortality rates.

“Early psychiatric assessment and intervention is essential.”

She notes that caregivers also need support and psychoeducation on how best to support patients in regaining function.

While being affected by a stroke is a frightening event, rest assured that there are treatments and therapies available to help you manage this condition – just remember that you need to seek medical help as soon as possible.

By TAN SHIOW CHIN This article is courtesy of Velocity Neurocentre, Sunway Medical Centre Velocity.

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7 stages of stroke recovery: Why home rehabilitation is important

A CT scan of a stroke patient’s brain, showing the affected area of their brain (in violet). The affected area will determine the type and extent of disabilities the patient will have. — Schering AG


By Matthew Teo Yong Chang

Stroke or a cerebral vascular accident (CVA) was the third leading cause of death in Malaysia in 2018, according to the Department of Statistics. The department reported that stroke caused 7.1% of all deaths in the country. However, two-thirds of those who have a stroke actually survive and will require rehabilitation.

The objectives of rehabilitation are to help survivors become as independent as possible and to attain the best possible quality of life. It is crucial as stroke survivors can lose the function of their affected limbs without rehabilitation, something we have observed in real life.

Even though the function of a stroke survivor’s affected limbs may seem lost after the stroke, our brain possesses a trait called neuroplasticity that can help the survivor regain the limb’s function.

Neuroplasticity enables the unaffected nerve cells (neurons) around the affected area of the brain to rewire and create new pathways around the affected area through repetition of physical and mental training, as well as regulated emotional feedback.

However, the extent for neuroplasticity varies in each individual. So, even though rehabilitation does not “cure” the effects of stroke, in that it does not reverse brain damage, rehabilitation can considerably help survivors achieve the best possible outcome in the long run.

Levels of disability
Rehabilitation, rehab, stroke, physiotherapy, activities of daily living, occupational therapy, Star2.com
Rehabilitation, rehab, stroke, physiotherapy, activities of daily living, occupational therapy, Star2.com Rehabilitation is aimed at regaining practical function for the patient, like opening a door latch, turning a tap or pushing a switch.

Strokes happen when a blood clot or bleeding (haemorrhage) restricts the blood supply to the brain, resulting in the brain being deprived of oxygen, which leads to the death of brain cells.

Usually, it is only one part of the brain that is damaged and this affects the type and degree of disability the survivor will experience. This also influences how much rehabilitation can help the survivor.

Generally, stroke can cause five types of disabilities:

• Paralysis, or problems controlling voluntary movement

• Disturbance of the senses, including pain

• Problems using or understanding language

• Problems with thinking and memory

• Emotional disturbances

It is also imperative to know the severity of the stroke before deciding on the rehabilitation plan. There are seven recognised stages of stroke recovery through which most survivors progress through:

Stage 1Flaccidity: No voluntary movement is observed.

Stage 2Spasticity appears: Spasticity refers to the continuous contraction of muscles, which interferes with normal movement, speech and gait, and causes the arm or leg to make small involuntary jerky movements.

Stage 3Increased spasticity: The e arm or leg becomes more spastic, and the muscles feel stiff and tight against external resistance.

Stage 4– Decreased spasticity: Spasticity of the arm or leg decreases and the limb begins to move more easily.

Stage 5Complex movement combinations: The movement of the limbs start becoming more coordinated and full movement begins to return.

Stage 6 Spasticity disappears: Muscle spasticity disappears and isolated joint movements are voluntary; however, spasticity may return if the patient is tired.

Stage 7Normal function returns: Movements return to normal.

Each stage requires different types of approaches and exercises for rehabilitation.

Home rehab
Rehabilitation, rehab, stroke, physiotherapy, activities of daily living, stretching, Star2.com
Rehabilitation, rehab, stroke, physiotherapy, activities of daily living, stretching, Star2.com A volunteer helps a stroke patient with her exercises during a therapy session. Stroke survivors are recommended to do flexibility exercises two to three times a week for the rest of their life.

The rehabilitation programme for stroke survivors involves a multidisciplinary healthcare team consisting of a rehabilitation physician, nurses, occupational therapist, physiotherapist, speech therapist, dietitian and clinical psychologist.

However, the most important members of the team are the patient and their caregivers. This is as rehabilitation should be done daily at home, not just during therapy appointments.

Battling stroke disabilities is not as simple a remedy as taking a pill from the doctor or attending a session with the therapist for an hour a week. It requires compliance to medication and the continuous effort to practice the therapies repetitively with strong determination!

Contrary to common belief, stroke rehabilitation can be offered in any setting without sophisticated equipment or technology.

The American Heart Association recommends that stroke survivors perform aerobic exercises three to seven days per week, as well as strengthening, flexibility and neuromuscular exercises two to three days a week, for the rest of their life.

Training at home, in a familiar environment, by adapting and using utensils or tools at home is more meaningful than the therapeutic remedial therapy received at institutionalised centres.

For instance, toilet training at a hospital ward is not as useful as toilet training in your own home, as you will eventually be going home and using that toilet, rather than the hospital’s toilet.

After all, the ultimate goal of rehabilitation is to promote optimal functional independence in the survivor’s own living environment.

Besides, providing therapy in the home environment supports continuity of care, provides a relevant environment for daily function, and encourages patients to develop problem-solving skills.

Some of the other benefits of home rehabilitation for stroke include:

• Early discharge from the hospital to return to the comfort of your own home.

• Avoiding hospital-acquired pneumonia and other illnesses due to a shorter stay.

• Reducing the cost of care.

• Preventing deterioration and promoting health through physical activity.

• Preventing falls, which are common among older patients and can cause additional long-term disability.

Barriers to home rehab

The main barriers towards rehabilitation in stroke are a lack of motivation and apathy towards recovery. Most stroke survivors stop coming for their treatment regime after a period of rehabilitation because they do not see any significant improvement.

Over a period of time, they will begin to learn helplessness and compensate themselves – mostly incorrectly – for their abnormal postures and movement, leading to non-compliance in rehabilitation.

Poor awareness among the public about the different roles of the different therapists in stroke rehabilitation could also be another barrier in rehabilitation.

In addition, the lack of trained therapists in Malaysia for stroke rehabilitation is also another factor, as it contributes to increased cost of hiring in-house therapists for home rehabilitation due to their scarcity.

Matthew Teo Yong Chang is a lecturer in the School of Occupational Therapy at the Perdana University Graduate School of Medicine. This article is courtesy of Perdana University. For more information, email starhealth@thestar.com.my. The information provided is for educational and communication purposes only and it should not be construed as personal medical advice. Information published in this article is not intended to replace, supplant or augment a consultation with a health professional regarding the reader’s own medical care. The Star disclaims all responsibility for any losses, damage to property or personal injury suffered directly or indirectly from reliance on such information.

Stroke Hand Exercises: For every stage of recovery


https://youtu.be/gDxyQGyOx_0

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Post-Stroke Exercises (Part 1: Upper Limb)


A physiotherapist explains safe lower limb exercises for stroke patients This video is brought to you by Singapore General Hospital.

https://youtu.be/3GbpbuwcWDk

Post-Stroke Exercises (Part 2: Lower Limb)


https://youtu.be/BM0P-iLSlbs

Stroke Exercises for Arm & Hand with Little to No Strength-for Home

"Famous" Physical Therapists Bob Schrupp & Brad Heineck demonstrate stroke exercises you can do in your own home for the arm and hand that has little to no strength.
https://youtu.be/DoR9H9zuJPY

Stretches For Hand Spasticity - Best Stroke Recovery Hand Exercises

  https://youtu.be/dBWRuy_hdoc



Best Stroke Recovery Hand Exercises - Stage 1


https://youtu.be/ZKR1nOtCNKU

Best Stroke Recovery Hand Exercises - Stage 2


https://youtu.be/oZrQU72dGO0

Best Stroke Recovery Hand Exercises - Stage 3

https://youtu.be/zpseq7i4_7A

 Taking Care Of Your Gut Is Key To Stronger Immunity



Taking Care Of Your Gut Is Key To Stronger Immunity | The Star


Others: One minute exercise cures: https://mp.weixin.qq.com/s/dACU6EJm66ZYSBMvO7byfA


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https://youtu.be/sFM-ip_WxTM
- Upper Limb Exercises

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Recognition and Management of Stroke



Rehabilitation key to improving health


DAEHAN Rehabilitation Hospital Putrajaya offers customised rehabilitation services that focus on intensity and discipline to give patients with neurological and orthopaedic disabilities optimal results.

Strokes and other neurological disabilities often leave individuals with lasting and damaging effects that can greatly impede their daily functions.

This brings to light the need to raise awareness on the crucial and beneficial role rehabilitation can play in the lives of such patients.

According to Dr Fazah Akhtar, studies have shown that early and high-intensity rehabilitation has given patients better outcomes.

“Certain neurological conditions such as strokes and traumatic brain injury have a window period of best recovery after the event,” said Dr Fazah.

“If an individual were to undergo high-intensity inpatient rehabilitation in a specialised hospital or unit, the recovery and functional outcomes of the patient have shown to be better than those who do not receive such treatment.”

Understanding this approach, Daehan Rehabilitation Hospital Putrajaya offers South Koreanstyled rehabilitation services in which they are on a one-on-one basis and are personalised to specifically match the needs of the individual.

Besides stroke patients, they also manage cases of traumatic brain injuries, hypoxic brain injuries, brain tumours, spinal cord injuries, musculoskeletal conditions and other complex conditions that require multidisciplinary rehabilitation.

With an emphasis on intensity and discipline, the inpatient rehabilitation programmes are planned and targeted for a duration of three months with extensions as needed.

A programme’s daily schedule usually features several rehabilitation sessions, starting at 9am and end at 5pm.

In addition, parts of the programme are practised in open and spacious therapy areas such as the gymnasium to enhance engagement and social interactions between patients.

This forms a support group system and such peer encouragement has seen a positive impact on the programme, says Dr Fazah.

All this is further augmented by technological advancements such as gait robotics, computerbased therapy, individualised hydrotherapy, and anti-gravity treadmills.

Their full list of therapy programmes includes physiotherapy, occupational therapy, functional electrical stimulation (FES), pain therapy, speech therapy, dysphagia rehabilitation, computerised cognitive function therapy, activities for daily living (ADL) training, return to work training, pulmonary rehabilitation, machine treatment, gait training with special equipment, robot-assisted gait trainer, hydrotherapy treadmill, and anti-gravity treadmill.

Meanwhile, their facilities and services include an emergency department, room and board, imaging department, specialist clinic, daycare service, inpatient and outpatient services, and outdoor therapy.

While Daehan Rehabilitation Hospital Putrajaya only offers its services to adults at this point, there are plans to expand to paediatrics rehabilitation soon.

Certain neurological conditions such as strokes and traumatic brain injury have a window period of best recovery after the event.

-Dr Fazah Akhtar

Others:

SBS - Sure Boh Singapore
 
·Founding Father Lee Kuan Yew's famous quote:

Founding Father Lee Kuan Yew's famous quote. I'm surprised it took them 65 minutes. I would have apologised straight away after he says "STOP IT!