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Showing posts with label medicines. Show all posts
Showing posts with label medicines. Show all posts

Thursday, April 6, 2023

How dangerous are India’s generic drugs? Very

 

India relies on the weak oversight of developing countries that make up the bulk of its exports – that’s how it can continue to push substandard and often deadly medicines there. — Bloomberg

 

FOR a nation that seeks to claim the mantle of “pharmacy to the world,” India is scandalously short on regulatory oversight.

In the last six months, its generic cough syrups have killed dozens of children, its eye drops have caused blindness and its chemotherapy drugs have been contaminated.

The children who died – mostly under the age of five years – were given Indian-made over-the-counter products contaminated with industrial solvents and antifreeze agents that are fatal in even small amounts.

The eye drops that contained extensively drug-resistant bacteria? So far 68 patients across 16 US states have been affected. Three people died, several had to have their eyeballs removed, some went blind, the Centres for Disease Control and Prevention reported on March 21.

The Indian company, Global Pharma Healthcare, issued a voluntary nationwide recall for the drops. India is the largest provider of generic medicines, producing 20% of the world’s supply, according to the government’s Economic Survey.

Its US$50bil (RM220bil) drug-manufacturing industry exports medicines to over 200 nations and makes 60% of all vaccines. It boasts “the highest number” of US Food and Drug Administration or FDA-compliant plants outside America, and indeed, some of its generic pharmaceutical companies produce high-quality medicines.

That may well provide consumers with a level of comfort, but history suggests it is unwise to trust that feeling.

The latest drug recalls just add to a long line of scandals that have tainted the sector.

In 2013, a US subsidiary of major Indian drug manufacturer Ranbaxy Laboratories Ltd pleaded guilty to US federal criminal charges and agreed to pay US$500mil (RM2.2bil) lion for selling adulterated generic drugs, fabricating data, and committing fraud. Serious flaws in the FDA compliance regime allowed these breaches to go undiscovered, until a years-long investigation laid bare the endemic corruption.

A generic drug made in India and modelled on Lipitor sold in the US to treat high cholesterol, for example, was contaminated with shards of blue glass, as journalist Katherine Eban documented in her book, Bottle of Lies: The Inside Story of the Generic Drug Boom. Her book draws in part on the experience of whistleblower Dinesh Thakur, who worked at Ranbaxy.

You would think such a damning indictment would prompt India to develop a safer, better pharmaceutical oversight regime. Think again.

The systemic fraud exposed by the investigation – where data was routinely falsified to fool inspectors, increase production and maximise profit – did not result in a regulatory overhaul.

Still, a two-day “brainstorming session” held in February appeared to acknowledge the system’s inherent weaknesses, with Health Minister Mansukh Mandaviya telling participants India needed to “move from generic to quality-generic drugs.”

Discussions involved “how to make the country’s drugs regulatory systems transparent, predictable and verifiable,” according to a health ministry media release.

Consumers shouldn’t hold their breath, though. A national law on drug recalls has been under discussion since 1976 without resolution, and the government – at least publicly –remains in denial: Since the Ranbaxy scandal, Thakur has campaigned for the reform of India’s main regulator, the Central Drugs Standard Control Organisation, and, with lawyer T. Prashant Reddy, has written his own book, The Truth Pill: The Myth of Drug Regulation in India, which was published in October.

They note that adulterated Indian drugs aren’t just killing children in developing-world export markets like Gambia and Uzbekistan. They’re also killing children at home: In 2019, at least 11 infants died in the state of Jammu because of cough syrup containing diethylene glycol. 

The World Health Organisation (WHO) sent alerts in October and January, asking for the cough medicine to be removed from the shelves. (It also issued a warning last year for cough syrups made by four Indonesian manufacturers sold in that country, where 203 children died in similar circumstances.)

Maiden Pharmaceuticals, whose medicines were sold in Gambia and linked by the WHO to the deaths of at least 70 children, has denied wrongdoing. And India’s regulator rejected the WHO’s findings, saying no toxic substances had been found in samples taken from Maiden’s plant. 

It shouldn’t have taken more deaths for Prime Minister Narendra Modi’s administration to act. The red flags have been there for years. What’s lacking is political will, and transparency. The FDA publishes different reviews of new drug applications on its website, along with detailed notes. 

So why does contamination with such deadly substances occur so regularly?

“The simple answer is that Indian pharmaceutical companies quite often fail to test either the raw materials or the final formulation before shipping it to market,” Thakur said.

India relies on the weak oversight of developing countries that make up the bulk of its exports – that’s how it can continue to push substandard and often deadly medicines there.

In the absence of a global framework for pharmaceutical safety, what can be done to make the generic drugs that consumers around the world have come to rely on safer and effective?

For a start, the WHO’s prequalification programme, which facilitates the purchase of billions of dollars’ worth of medicines through international agencies such as Unicef, must be overhauled. Then there’s the question of holding these companies to account for the harm they cause inside and outside India via legal avenues and victims’ compensation. — Bloomberg 

- Ruth Pollard is a Bloomberg Opinion columnist. The views expressed here are the writer’s own.

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Tuesday, August 16, 2022

LIVER HEALTH: to Maintain a Balanced Life for overall well-being

4 Foods That Protect Liver Health

 

4 Worst Damaging Habits- Thomas DeLauer

Liver Health: 4 Worst Damaging Habits- Thomas DeLauer… http://www.ThomasDeLauer.com for all your business, health, and fitness answers. The number one over the counter medication responsible for wrecking our livers is acetaminophen. Join Celebrity Trainer, Author & Organic Foods Expert, Thomas DeLauer to find out what other habits may be contributing to the health and function of our livers. Learn how the liver plays a big role in our metabolism, how we burn fat, how we get into shape, and detoxification.

1) Too much self-medication: 
One of the main functions of the liver is to break down substances that we take by mouth, including medications, herbs and supplements. This process usually takes place efficiently and without causing any harm. When new medications are developed, they are extensively tested to make sure they are safe before being approved for general use. Acetaminophen, when used as directed, is extremely safe even for people with liver disease. However, taking too much acetaminophen at once, or taking a high dose of acetaminophen continuously over several days can cause damage to the liver.
 
How it Damages the Liver: A dose of Tylenol is absorbed by the gastrointestinal system and released into the bloodstream, where it alleviates pain and symptoms of fever. The liver filters the blood, which is responsible for metabolizing Tylenol into compounds that can be excreted by the body. About 90% is metabolized into harmless substances and excreted in the urine by the kidneys. Another 2% is removed without being metabolized. Between 5-10% is metabolized into a toxic compound called N-acetyl-p-benzoquinoeimine (NAPQI). Normally, the liver can safely remove NAPQI by combining it with gluthathione and converting it into a water-soluble product that is excreted in bile. However, after an overdose, the liver does not have enough gluthathione to combine with the NAPQI. Excess amounts of the toxic chemical cause rapid cell death, necrosis, tissue damage, and potentially deadly acute liver failure. (1,2,3) 
 
2) Alcohol abuse: 
The liver can only handle a certain amount of alcohol at any given time, so if you drink more than the liver can deal with by drinking too quickly, or drinking too much, your liver cells struggle to process it. When alcohol reaches the liver, it produces a toxic enzyme called acetaldehyde, which can damage liver cells and cause permanent scarring.
 
 3) Smoking: 
Though cigarette smoke does not directly come into contact with the liver, it does indirectly affect the liver. The chemicals in cigarette smoke eventually make their way to the liver. These chemicals cause oxidative stress on the liver, which leads to damage to the liver cells and fibrosis. Oxidative stress is involved in the aging of all the organs of the body. Oxidation produces free radicals that damage the cells of the body.
 
 4) Lack of Sleep: 
If you want to keep your body — and particularly your liver ­– in good condition, it is important that you get enough sleep. During sleep, the body repairs and renews its cells, so lack of sleep will interfere with that. In turn, if the liver cannot repair and renew itself as you sleep, it can’t function properly when you’re awake. A study published in the Journal of Anatomy found that sleep deprivation can cause oxidative stress to the liver. It was found that livers weren’t processing fat efficiently and instead allowed fat to accumulate (which proves that the body cannot function well without a properly working liver) (8) 
 
References:
 1) Acetaminophen and Liver Injury: Q & A for Consumers. (n.d.). Retrieved from http://www.fda.gov/ForConsumers/Consu...
 
2) How Does Tylenol Cause Liver Damage? (n.d.). Retrieved from https://www.schmidtlaw.com/how-does-t...
 
3) How Does Tylenol Cause Liver Damage? (n.d.). Retrieved from https://www.schmidtlaw.com/how-does-t...
 
4) Maher, J. (1997). Exploring Alcohol’s Effects on Liver Function. Retrieved from https://pubs.niaaa.nih.gov/publicatio...
 
5) Alcohol — Love Your Liver. (n.d.). Retrieved from http://loveyourliver.com.au/alcohol/
 
6) Heavy smoking and liver. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/arti...
 
7) 5 Common Habits That Damage Your Liver. (n.d.). Retrieved from http://www.healthyandnaturalworld.com...
 
8) Sleep deprivation predisposes liver to oxidative stress and phospholipid damage: a quantitative molecular imaging study. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/arti...
 
9) Liver Health: The Role of Turmeric in Fatty Liver Disease. (n.d.). Retrieved from http://www.globalhealingcenter.com/na...
 
10) Turmeric Can Reduce Risk of Fatty Liver Disease. (n.d.). Retrieved from https://hepfree.nyc/turmeric-can-redu...

 

 Why Healthy Liver Function is Essential to Maintain a Balanced Life

 


The liver is extraordinary! Responsible for over 500 functions, it's important that the liver is needed for overall health and wellbeing.

The liver function is quite extraordinary. The liver is made up of 2 lobes and is located on top of the stomach. As the “Commanding General” of the body, it is also the largest solid organ with over 500 important functions. To name a few liver functions, it regulates chemical levels in the blood, excretes bile, promotes healthy absorption and digestion, and ensures good circulation of qi, our vital energy.

As we can see, it’s imperative that the liver functions properly for overall health and wellness in the body. We share more about liver functions, what happens when issues arise, and herbal remedies to help maintain optimal health.

What is the Function of the Liver?

A white senior man with gray hair exercising outdoor on a beach

One vital liver function is to regulate the distribution of our life force for organs nourishment.

Most people know the liver as one of our vital organs. While it’s true from the perspective of modern anatomy, the liver has a vast basis of functions that affect the other organs. Let’s take a look at the different liver functions based on Western medicine and Traditional Chinese Medicine (TCM).

Liver function in Western medicine

There are many things that our liver does on the daily basis. It’s considered the largest organ and gland inside the human body. Interestingly, it’s the only organ that can regrow and replace its tissue.

Inside a liver, there are hundreds of tasks on progress every single day. But mostly, here are five major functions of the liver, based on its anatomical structure.

Production of bile

Made of mainly bilirubin, cholesterol, and bile acids, bile is essential for our digestion. It breaks down fats into fatty acids and turns ammonia, which is poisonous, into the urine.

Regulation of blood levels

The liver helps to regulate our blood of amino acids, regulates our blood for proper clotting and healing, helps to clear the body of drugs or harmful substances, and helps to store resist infections by removing bacteria from the bloodstream.

Conversion of excessive glucose

The liver converts excessive glucose (sugar) into glycogen. This is used for storage that can be converted back for energy and additional glucose.

Clearance of bilirubin

Our liver also works to ensure that we don’t have excessive bilirubin from our red blood cells. Having this condition makes our eyes and skin yellow.

Stores vitamins and minerals

The liver also stores vitamins A, D, E, K, and B12. The liver is also the storage center of iron and copper.

Liver function in TCM

In TCM, the liver is one of the five Zang organs with one primary function: to store and distribute jing (essence) and qi. Rather than referring to liver in anatomy, TCM regards liver as a part of a complex web connecting multiple systems and organs. TCM sees liver functions as essential in four main areas.

Beyond its anatomical concept, our liver is a part of a complex web connecting multiple systems and organs. According to TCM, the main liver function is to control the movement of qi that sustains the organs and tissues of the body.

TCM sees liver function as essential in four main areas:

  • Distribution of qi
  • Regulation of digestive system
  • Management of emotional health
  • Modulation of the female reproductive system

The balance of qi in our liver will ensure the proper functioning of other organs inside the body. Therefore, we all need a healthy liver to function and thrive.

Problems with Poor Liver Function

In today’s fast-paced society, people who struggle to achieve work-life balance may be more susceptible to poor liver function and imbalances. Here are some problems that can arise with liver issues.

Liver disease

Western perspective: According to the Centers for Disease Control and Prevention, liver disease, also called hepatic disease, affects 4.5 million Americans. The result of substance abuse, obesity, autoimmune diseases, cancer, or viruses such as hepatitis can lead to the disruption of the liver. This is very serious that can lead to a life-threatening condition called cirrhosis. Over time and if untreated can lead to hepatic encephalopathy, esophageal varices, abdominal ascites, liver failure, or liver cancer.

Issues with the liver can also be genetic such as Hemochromatosis, Wilson’s Disease, and Alpha 1 Antitrypsin Deficiency. Hemochromatosis is signified as an iron disorder where the body absorbs too much iron from the food you eat; whereas Alpha 1 Antitrypsin Deficiency is the lack of a certain enzyme, and Wilson’s Disease prevents the body from removing copper in the liver.

Early awareness and a healthy lifestyle — such as limiting alcohol intake, adapting to a healthy diet, and doing regular exercises — are essential to keep the liver functioning properly. Some symptoms to look out for include yellowish and/or itchy skin, swelling of the body, excessive tiredness, pale stool, dark urine, or a loss of appetite, to name a few symptoms. Seek guidance from your doctor who can further assess your symptoms.

TCM perspective: TCM regards the liver as an army general of our body that regulates the movement of ‘qi’ to all organ systems. That’s why any imbalances in the liver can affect the activities of other organs and cause many health issues.

Digestive system disorders

An ill handsome caucasian man lying on a sofa while touching his forehead

Stomach issues can be related to problems with the liver.

Western perspective: During the early onset of liver diseases like cirrhosis, a person may experience appetite loss. This can make them lose more weight. According to a 2014 study, around 80% of liver cirrhosis patients are having at least one symptom of gastrointestinal diseases (GI). The symptoms include abdominal pain, bloating, diarrhea, belching, and constipation — leading to malnutrition. The causes could be raised toxin levels and insulin resistance due to problems in liver function.

TCM perspective: From a TCM perspective, a disrupted balance in the liver, spleen, stomach, and gall bladder causes digestive system disorders. As a result, people who are prone to qi imbalances are likely to present with various symptoms, such as belching, heartburn, a poor appetite, and a thin white- or yellow-colored tongue coating.

TCM uses a classical formula known as 柴胡舒肝散 (Chai Hu Shu Gan San) to treat imbalances in the stomach and liver. It consists of several ingredients that work in tandem to regulate stomach and liver imbalances. The most basic ingredients of this formula are licorice root, bupleurum, bitter orange, aged tangerine peel, nutgrass galingale rhizome, Sichuan lovage root, and peony root.

Combining Toosendan fruits and Corydalis rhizome with this formula can relieve pain by improving the effect on liver qi. Meanwhile, adding decocted inula flower and hematite — the natural mineral form of iron oxide — can promote better downward movement of qi and relieve the counterflow.

Physical and emotional disorders

Western perspective: Liver dysfunction can be hard to diagnose since there are almost no visible symptoms early on. However, as the liver function becomes more impaired, it will cause physiological changes like an electrolyte imbalance and portal hypertension. In turn, patients will start experiencing physical and emotional symptoms. These include muscle cramps, breathlessness, itchy skin, trouble sleeping, depression, andanxiety

TCM perspective: Our emotional and physical health are interconnected. For example, excessive anger or irritability is linked to various ailments. This includes dizziness, headaches, dry mouth, and redness of the face and eyes.

Similarly, TCM also believes that emotional imbalances can act as both the symptoms and causes of physical problems. Liver imbalances, specifically, link to anger, irritability, and mental health conditions such as sleeplessness, ddepression,and chronic stress.

A sleep formula known as Suan Zao Ren Tang is especially effective in treating insomnia. Sour jujube seeds — one of the ingredients of this classic formula — is particularly beneficial for improving sleep quality. It works by calming the mind, preventing excessive sweating, nourishing the liver, and soothing the nerves .

Women’s health disorders with the liver

Two smiling young white women riding bicycles in the city

A healthy liver means more energy, regulated periods, and less PMS symptoms. You are ready to face more adventures.

Western perspective: As a part of the endocrine system, liver dysfunction can impact hormonal balance. In women, chronic liver disease may cause amenorrhea (missing periods) and  infertility. This can be triggered by low testosterone along with high estrogen and prolactin levels.

TCM perspective: An unbalanced liver can cause irregular periods, premenstrual syndrome (PMS), mood disorders, fatigue, fever and/or chills, abdominal pain, growth of benign masses in the uterus called fibroids, and early menopause..

Another important role of the liver is the storing of blood as well as regulate blood volume in the body. During rest, blood requirement in organs and structures is less and excess blood is channeled to the liver for storage. When there is activity, demand for blood increases and the liver transports blood to the respective organs to meet these needs. In the case of liver blood deficiency, organs fail to receive adequate nourishment which can result in symptoms such as giddiness, weakness in limbs, insomnia, and scanty periods in women or even amenorrhea. When blood cannot be stored in the liver effectively, the circulation of blood becomes unpredictable, leading to either bleeding from the orifices or heavy menstruation in females.

Visual disorders

Western perspective: Eye and visual issues can also be connected to liver disorders. Conditions such as Xanthelasma signified by a yellowish bubble on the eyelid, jaundice, cataracts, or Wilson’s disease may suggest a disrupted liver function.

The liver is also responsible for the production and storage of vitamin A. Because of this, problems in the liver can cause nyctalopia — an inability to see clearly in dim light or at night — and dry eye disease.

TCM perspective: Every organ has an association with a sense organ. The liver is most closely linked to the health of our eyes. Any unpleasant signs of the eyes can therefore be used to assess the health status of the liver. TCM believes that liver blood can travel upwards to nourish eye structures and gives the eyes capacity to see. A deficiency in liver blood may lead to eye issues such as blurred vision, myopia and eye floaters. On the other hand, excess liver heat can manifest in symptoms like red and bloodshot eyes, painful eyes which may be accompanied by a burning sensation.

A herbal tonic prepared using goji berries can nourish the liver, thus help improve your vision. It also improves circulation and strengthens your immune system.

How to Maintain a Healthy Liver

Several cubes of dried poria mushrooms on a copper plate 

Several cubes of dried poria mushrooms on a copper plate Poria mushroom is one of the many TCM ingredients that can boost liver health.

A healthy liver function is essential for your overall well-being. Maintaining a healthy lifestyle is important for the body as well as the liver. This includes regular exercise, moderate-to-no drinking or drug use, practicing safe sex, and eating healthy foods. A diet rich in green tea, vegetables, legumes, whole grains, nuts, oats, fatty fish, and limited salt, sugar, saturated fats, and refined carbs is important for liver health.

A classic formula called ‘Free and Easy Wanderer (Xiao Yao San)‘ contains eight ingredients. They are bupleurum, peppermint, Chinese Angelica, ginger root, licorice root, Poria mushrooms, white atractylode, and white peony roots. Xiao Yao San is a classical TCM formula that soothes the liver, strengthens the spleen and nourishes blood. It clears “liver stagnation” which contribute to stress, mood swings, pain, irritability, constipation, abdominal upset, premenstrual syndrome (PMS), and irregular periods.

Supplementation can help to enhance the healthy liver, such as  Wild Yunzhi Powder and LLiva Max, containing medicinal fungus, stout camphor fungus (niu chang chih). These formulations can also improve the body’s resistance to disease, promote vitality, and enhance the respiratory system. According to studies conducted on mice, antrodia cinnamomea, has been widely to treat diseases such as liver disease, drug and food intoxication, diarrhea, and certain cancers.

Many issues that arise with the liver are preventable or reversible. However, if you are experiencing any symptoms related to imbalances in the liver, you should seek the advice of a doctor or TCM practitioner. These professionals can assess your situation and prescribe remedies for your specific issues. 

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References

  1. John Hopkins Medicine. 2021. Liver :Anatomy and Functions. [Accessed on December, 6 2021]  
  2. Medline Plus. 2021. Bile. [Accessed on December, 6 2021]  
  3. NCBI. 2001. Risk factors for primary biliary cirrhosis in a cohort of patients from the united states. [Accessed on December, 6 2021]  
  4. NCBI. 2013. Liver Disease in Women: The Influence of Gender on Epidemiology, Natural History, and Patient Outcomes. [Accessed on December, 6 2021]  
  5. Northwell Health. 2021. Understanding liver disease in women. [Accessed on December, 6 2021]  
  6. American Association for the Study of Liver Diseases. 2021. Clinical examination: Eyes. [Accessed on December, 6 2021]  
  7. Medline Plus. 2021. Liver Diseases. [Accessed on December, 6 2021]  
  8. NPR. 2021. Sharp, ‘Off The Charts’ Rise In Alcoholic Liver Disease Among Young Women. [Accessed on December, 6 2021]  
  9. CDC. 2021. Chronic Liver Disease and Cirrhosis. [Accessed on December, 6 2021]  
  10. NIH. 1999. National Institute on Alcohol Abuse and Alcoholism . [Accessed on December, 6 2021]  
  11. Arizona Liver Health. 2021. What are genetic liver diseases?. [Accessed on December, 6 2021] 
  12. Karger. 2017. Liver in the Chinese and Western Medicine. [Accessed on December, 15 2021]
  13. Karger. 2017. The Brief Theory of Viscus and Its Manifestations in Traditional Chinese Medicine. [Accessed on December, 15 2021]
  14. US National Library of Medicine. 2014. Gastrointestinal dysfunction in liver cirrhosis. [Accessed on December 15, 2021]
  15. Wolters Kluwer. 2015. Impact of physical and psychological factors on health-related quality of life in adult patients with liver cirrhosis: a systematic review protocol. [Accessed on December 15, 2021]
  16. National Library of Medicine. 2019. A Study of Hormonal Abnormalities in Chronic Liver Disease. [Accessed on December 15, 2021]
  17. International Journal of Medicinal Mushrooms. 2018. Immunomodulatory Effects of the Stout Camphor Medicinal Mushroom, Taiwanofungus camphoratus (Agaricomycetes)–Based Health Food Product in Mice. [Accessed on January 25, 2022]

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Why Healthy Liver Function is Essential to Maintain a Balanced Life https://www.allthingshealth.com/en-us/general-health/digestive-health/healthy-liver-function/
 
 
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Saturday, January 25, 2020

Containing Novel Coronavirus Outbreak in China: public gatherings cancelled, cities under lockdown ..



Live: Press conference on the novel coronavirus outbreak国家卫健委通报疫情和防控工作最新进展

 
https://youtu.be/xQxOeUA0jRQ 


Coronavirus Latest Live Update from Shenzhen China.

  https://youtu.be/ZgnjiEd4gVU

Malaysian Embassy in Beijing establishes Emergency Response Team


https://youtu.be/6cuE3RAJJQs

https://youtu.be/4yC8gVoNkUs

Chinese medics give up new year celebrations to head to coronavirus quarantine zone

https://youtu.be/VbA2PRYsakA

A 46-year-old man has become the first patient in east China's Zhejiang Province to recover from the coronavirus. The man, surnamed Yang, left the hospital on Friday after undergoing treatment for a week. The patient had been living in Wuhan for a long time. Yang will continue to visit the doctors for regular checkups.

19 Chinese provinces, municipalities launch highest-level emergency response

https://youtu.be/7Tc4HpDGwaE

Over 1,317 coronavirus cases have now been confirmed globally. So far, 42 infected people have died in China. A total of 19 provinces and municipalities in China, including Beijing, Shanghai and Jiangsu provinces have declared the highest level of public health emergency to combat the coronavirus outbreak. 

Some traditional holiday celebrations, such as temple fairs and cultural performances and other public gatherings have been canceled. At least 16 cities in the worst-hit province of Hubei have suspended public transportation, including local buses, subways, ferries and long-distance coaches. 

Around 450 military medical personnel have been deployed in the province, while nearby Sichuan Province has also sent 135 medical staff members. China's Finance Ministry has allocated a total of one billion yuan to support Hubei. 

In addition, the provincial capital of Wuhan is building a special hospital on the outskirts of the city to treat patients with the virus. The 1,500-bed facility is expected to open by February 3. Subscribe on YouTube: https://goo.gl/lP12gA

11 million people are under lockdown in Wuhan

https://youtu.be/RTbJ2wKILJM

Wuhan lockdown leads to empty streets, train stations

  https://youtu.be/57GeEbPM8AQ

https://youtu.be/ltcV3Q-1ztw

China shuts down multiple cities in an effort to curb coronavirus outbreak

https://youtu.be/463-Ep139u4

The Science of Viral Outbreaks / Global Firms on Strategy amid Uncertainty

https://youtu.be/AqlYyOe96mg

Is travel to China safe?

Wuhan is closed to travelers.  

The CDC advises travelers to China to:

  • Avoid contact with sick people.
  • Avoid animals, animal markets, and products that come from animals.
  • Wash your hands often with soap and water, or use an alcohol-based sanitizer if that’s not available.
  • Seek medical care right away if you have a fever, cough, or a hard time breathing. Tell your health care professional about your travel.

What are the symptoms, and how is the virus diagnosed?

China created a test for the virus and shared that information with other countries. The CDC has developed its own test.

Symptoms include a fever, coughing, and shortness of breath. They may appear 2 to 14 days after you’re exposed to the virus. What is the source of the virus, and how is it spread?

Health officials are not sure of the source of the virus yet or how easily it can spread. Coronaviruses are found in many different animals, including camels, cattle, cats, and bats. One research paper also suggested snakes as a possible source. The new virus may be linked to a seafood and live animal market in Wuhan that has since been closed

The virus can spread from person to person. Health officials are seeing this happen most often where people are close together and in health care settings. To date, 16 health care workers have been infected.

The CDC believes that severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), two other types of coronavirus, are spread through droplets when someone coughs or sneezes.

Is there a vaccine?

There is no vaccine, but the National Institutes of Health is working on one and hopes to begin testing in several months. That testing would be for safety. If it’s safe, there would be testing to see how well it works.

How is it treated?

There is no specific treatment for the virus. Patients are generally given supportive care for their symptoms, such a fluids and pain relievers. Hospitalized patients may need support with breathing.


Are you in danger of catching the coronavirus? 
5 questions answered :

1. Am I at risk?

Not now, because currently every case of the novel coronavirus is linked to Wuhan.

There are lots of different coronaviruses that group into three types. The common cold can be caused by both alpha and betacoronaviruses.

Coronavirus was never really taken that seriously until 2003, when a coronavirus jumped species – likely from bats to humans via civets – and led to SARS, or severe acute respiratory syndrome. This species-jumping ability of coronaviruses is being observed again, now in Wuhan at the seafood market. This coronavirus is in the betacoronavirus group. China has now put travel restrictions in place to limit spread from Wuhan.

2. What’s the big concern with this virus?

For the novel coronavirus from Wuhan, there is no vaccine, and we’re lacking a specific therapy. So it is key to limit spread through quarantine of infected individuals and by tracing of contacts.

3. What is so unusual about this coronavirus?

This is a coronavirus that has never been seen in humans before. It likely came from bats, and it’s much more serious than the common cold coronavirus. This is only the third time that we’ve seen a coronavirus jump species from animals to humans. The concern is that this coronavirus is going to behave like SARS and MERS, or Middle East respiratory syndrome in 2012, both of which were serious.

4. Do the deaths appear to be among people of a certain age?

Many were in older men with pre-existing conditions.

5. How can I stay safe?

First of all, you need not be concerned about catching this right now. Practice the same precautions that you would to prevent catching a cold. Viruses that cause the common cold are on surfaces of handrails and doorknobs, so wash your hands, use sanitizers and stay home when you are sick.

Read more:


Salute to Wuhan citizens for their sacrifice

Rationality and unity needed in fight against virus

Zhou Xianwang, the mayor of Wuhan, Central China's Hubei Province, where the ongoing spread of coronavirus pneumonia began, said at a press conference on Sunday night that more than 5 million people have left the city because of the Spring Festival and the epidemic. The news came as quite a shock.

Wuhan pneumonia response reflects progress in China's system

More adjustments and improvements are needed in China's governing system. In the Wuhan pneumonia case, is it possible to release information more timely and comprehensively? It will prove to be a test of China's system. But more and more Chinese people believe the system will stand the test and improve itself amid the challenge.

Wuhan pneumonia a wake-up call for basic Chinese research

Time is needed for basic research. But times waits for no one. Any attempt to seek quick success and instant benefits must be avoided. However, it is time for China to increase investment, focus on talent training, team building and policy adjustments in this field.

Virus attracts global efforts

The World Health Organization (WHO) is scheduled to convene a special meeting in Geneva, Switzerland on Wednesday to discuss whether the epidemic caused by a novel coronavirus detected in China and now spreading across the world should be declared a global emergency.

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